My guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication. #HubermanLab #Science #Neuroscience Thank you to our sponsors AG1 (Athletic Greens): 🤍athleticgreens.com/huberman Levels: 🤍🤍levelshealth.com/huberman Eight Sleep: 🤍🤍eightsleep.com/huberman InsideTracker: 🤍🤍insidetracker.com/huberman Supplements from Momentous 🤍🤍livemomentous.com/huberman Huberman Lab Premium 🤍hubermanlab.com/premium Social & Website Instagram: 🤍🤍instagram.com/hubermanlab Twitter: 🤍twitter.com/hubermanlab Facebook: 🤍🤍facebook.com/hubermanlab TikTok: 🤍🤍tiktok.com/🤍hubermanlab LinkedIn: 🤍🤍linkedin.com/in/andrew-huberman Website: 🤍hubermanlab.com Newsletter: 🤍hubermanlab.com/neural-network Dr. Eddie Chang Support research in the Chang Laboratory: 🤍changlab.ucsf.edu/support-our-work Dr. Chang’s lab: 🤍changlab.ucsf.edu Academic profile & publications: 🤍profiles.ucsf.edu/edward.chang UCSF clinical profile: 🤍🤍ucsfhealth.org/providers/dr-edward-chang Articles Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria: 🤍bit.ly/3sjv5Cx Articles in the News Tapping Into the Brain to Help a Paralyzed Man Speak: 🤍nyti.ms/3f0AM5c How Brain-Computer Interfaces Could Restore Speech and Help Fight Depression: 🤍on.wsj.com/3f1iBMH Decoded Brain Signals Could Give Voiceless People A Way To Talk: 🤍n.pr/3gujhdP Timestamps 00:00:00 Dr. Eddie Chang, Speech & Language 00:03:00 Levels, Eight Sleep, InsideTracker, Momentous Supplements 00:07:19 Neuroplasticity, Learning of Speech & Environmental Sounds 00:13:10 White Noise Machines, Infant Sleep & Sensitization 00:17:26 Mapping Speech & Language in the Brain 00:24:26 Emotion; Anxiety & Epilepsy 00:30:19 Epilepsy, Medications & Neurosurgery 00:33:01 Ketogenic Diet & Epilepsy 00:34:56 AG1 (Athletic Greens) 00:36:10 Absence Seizures, Nocturnal Seizures & Other Seizure Types 00:41:08 Brain Areas for Speech & Language, Broca’s & Wernicke’s Areas, New Findings 00:53:23 Lateralization of Speech/Language & Handedness, Strokes 00:59:05 Bilingualism, Shared Language Circuits 01:01:18 Speech vs. Language, Signal Transduction from Ear to Brain 01:12:38 Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations 01:17:37 Mapping Language in the Brain 01:20:26 Plosives & Consonant Clusters; Learning Multiple Languages 01:25:07 Motor Patterns of Speech & Language 01:28:33 Reading & Writing; Dyslexia & Treatments 01:34:47 Evolution of Language 01:37:54 Stroke & Foreign Accent Syndrome 01:40:31 Auditory Memory, Long-Term Motor Memory 01:45:26 Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI) 02:02:14 Neuralink, BCI, Superhuman Skills & Augmentation 02:10:21 Non-Verbal Communication, Facial Expressions, BCI & Avatars 02:17:35 Stutter, Anxiety & Treatment 02:22:55 Tools: Practices for Maintaining Calm Under Extreme Demands 02:31:10 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media Huberman Lab is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Title Card Photo Credit: Mike Blabac - 🤍🤍blabacphoto.com
Every podcast I hope Andrew Huberman makes a video about already exists. so helpful
Dear Dr. Huberman,
This was one of the best segments that you have produced. As I was finishing my PhD in Neuropsychological, I was diagnosed with a Brain tumor (Astrocytoma grade lll) and then a resection, Temodar (14 months) and of course 6 weeks of radiation. This occurring in March 2003. The location was left parietal resulting in Gerstmann’s syndrome. You guys touched on so much in this segment and I was glad to hear someone vocalize that Broca’s area and Wernicke’s area were not set in stone. I always thought there was more to it! Thank you, Dr. Huberman for asking the question?
Speechless (rare to say this on a language topic? 😅. Just what I’m been thinking for few decades about if the neuroscientific books are updated. Now I don’t know what to do.. I think I’ll stick to this channel for ever ❤️ thanks to doctor Eddie, to amazing Andrew H and his team (there is one right?). From 🇯🇵 arigatou !
Augment brain speed? Study SERIOUSLY the piano or violin or cello.
Cerebellum wasting away - Can you help my friend???
Thank you. ❤.
i only need to be around someone with an accent and i automatically start speaking the same accent after 5 minutes.
Two childhood friends that seemingly dominated the science world… ❤
Z7MU6zrAXsM&t=1h38m26s 1:38:26 just want to learn now at 33
On augmentation: it would be useful to talk to a Sci fi author on that, perhaps one who's also a scientist within the subject (there's a lot of overlap). This is an area where the science and knowledge is catching up very quickly to what we are imagining (and what it's capable for us to imagine). The subject is being talked about a lot, but the implications are still primarily within the realm of literature. Cyberpunk 2077 shows that it's very much within the sphere of public thought, and it would be beneficial to discuss what's actually possible VS what's fantastical.
As a former stutter this was particularly interesting. I missed why or where in the podcast Dr. Chang mentioned not drinking coffee.
There seems to be something outside of your physical being that stimulates certain parts of the brain having to do with language and thought from what you describe - correct?
But it's not Deja Vu! It's the best way we can explain it to anyone who hasn't felt it.
I had a stroke and lost my ability to speak. Bracca and Wernicke question !!!
Lmao I straight up got an Andrew Huberman ad on a huberman video
Has anyone else noticed how Andrew, and several people in society, started to slightly hold and over-enunciate "sh" and "ch" in the last five or so years? I've also noticed that the letter "t" is starting to disappear, and generally speaking, adults sound like children when they talk. It's like there's no in-between... either I hear the sh/ch thing, the complete erasure of all t's OR people sound like my seven year old nephew, slurring everything together and not really enunciating anything. With everything else going on in the world, and the fact that not many other people seem to notice, I find it incredibly weird and unsettling.
*EDIT: Case in point - after listening for a while... I'm not attacking anyone's intelligence, I'm just pointing out an observation that Dr. Chang doesn't over-enunciate the sh/ch, but he kinda slurs everything together... like a kid. Not sure why my ears pick up on that.
Any episodes or studies on abstinence? Curious what a healthy male routeen looks like.
Look up the story of Mary Steenburgen after she had surgery in 2007 and how she developed a music skill in her head. That seems incredible.